Phosphatidylserine peroxidation/externalization during staurosporine-induced apoptosis in HL-60 cells

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NADPH Oxidase-dependent Oxidation and Externalization of Phosphatidylserine during Apoptosis in Me2SO-differentiated HL-60 Cells

From the Department of Environmental and Occupational Health, Department of Pharmacology, and Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, the Magee-Womens Research Institute, Pittsburgh, Pennsylvania 15213, the Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg 194223, Russia, the Department of Medical Ch...

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[Ethanol-induced apoptosis in human HL-60 cells].

The purpose of this study was to examine the effect of ethanol on apoptosis of human promyelocytic leukemia cell line HL-60 cells and search for a possible reason for reduced PMNs, monocytes, lymphocytes in the blood of alcoholics. Human promyelocytic leukemia cell line HL-60 cells was used as a model of apoptosis, with ethanol being the interfering factor. Qualitative and quantitative detectio...

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Lantadene A-induced apoptosis in human leukemia HL-60 cells

Objectives: Lantadene A (LA, 22β-angeloyloxy-3-oxoolean-12-en-28-oic acid) a pentacyclic, triterpenoid isolated from the leaves of the obnoxious weed, Lantana camara L. was evaluated for apoptosis induction in the human leukemia HL-60 cell line. Materials and Methods: The effect of LA on cell proliferation of HL-60 cancer cells was determined by using the MTT assay. The morphological effects of...

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Immunocytochemical Study on Microtubule Reorganization in HL-60 Leukemia Cells Undergoing Apoptosis

Background: Microtubules (MT) are important components of cell cytoskeleton and play key roles in cell motility mitosis and meiosis. They are also the targets of several anticancer agents which indicating their importance in maintaining cell viability. Microtubular reorganization contributing to apoptotic morphology occurs in normal and neoplastic cells undergoing apoptosis induced by cytotoxic...

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Norcantharidin Induces HL-60 Cells Apoptosis In Vitro

Norcantharidin (NCTD) is the demethylated form of cantharidin, which is the active substance of mylabris, and is known to have anticancer potentials. The aim of this paper was to assess the apoptosis-inducing effect of NCTD on HL-60 cells. Methods. The effects of NCTD were detected by flow cytometer on the cell toxicity, cell cycle, and apoptosis of HL-60 cells cultured in vitro. Results. After...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 2002

ISSN: 0014-5793

DOI: 10.1016/s0014-5793(02)02990-3